• Guzaev, A. P. Solid-Phase Supports for Oligonucleotide Synthesis. In: Curr. Protoc. Nucleic Acid Chem. Ed. Beaucage, S. L., Vol. 53, Unit 3.1, pp. 3.1.1-3.1.60, John Wiley & Sons: 2013. PDF

 

• Guzaev, A. P. and Pon, R. T. Attachment of Nucleosides and Other Linkers to Solid-Phase Supports for Oligonucleotide Synthesis. In: Curr. Protoc. Nucleic Acid Chem. Ed. Beaucage, S. L., Vol. 52, Unit 3.2, pp. 3.2.1-3.2.23, John Wiley & Sons: 2013. PDF

 

• Stiles, D. K.; Zhang, Z.; Ge, P.; Nelson, B.; Grondin, R.; Ai, Y.; Hardy, P.; Nelson, P. T.; Guzaev, A. P.; Butt, M. T.; et al. Widespread suppression of huntingtin with convection-enhanced delivery of siRNA. Exp. Neurology 2012, 233, 463-471. PDF

 

• Guzaev, A. P. Reactivity of 3H-1,2,4-dithiazole-3-thiones and 3H-1,2-dithiole-3-thiones as sulfurizing agents for Oligonucleotide Synthesis. Tetrahedron Lett.  2011, 52, 434-437. PDF

 

• Kumar, R. K., Guzaev, A. P., Rentel, C., Ravikumar, V. T. Efficient Synthesis of Antisense Phosphorothioate Oligonucleotides Using a Universal Solid Support. Tetrahedron 2006, 62, 4528-4534. PDF

 

• Guzaev, A. P. and Manoharan, M. A Conformationally Preorganized Universal Solid Support for Efficient Oligonucleotide Synthesis. J. Am. Chem. Soc. 2003, 125, 2380-2381. PDF

 

• Guzaev, A. P. and Manoharan, M. Selective Phosphate Protection: a Novel Synthesis of Double-labeled Oligonucleotides. Org. Lett. 2001, 3, 3071-3074. PDF

 

• Guzaev, A. P.; Bhat, B.; Balow, G.; and Manoharan, M. Synthesis of Chimeric Oligonucleotides Containing Internucleosidic Phosphodiester and S-pivaloylthioethyl Phosphotriester Residues. Nucleosides & Nucleotides 2001, 20, 1015-1018. PDF

​​

• Guzaev, A. P. and Manoharan, M. A Novel Protecting Strategy for Internucleosidic Phosphate and Phosphorothioate Groups. Nucleosides & Nucleotides 2001, 20, 1011-1014. PDF

 

• Doronina, S. O.; Guzaev, A. P.; and Manoharan, M. Efficient Synthesis of Oligonucleotide-Peptide Conjugates on Large Scale. Nucleosides & Nucleotides 2001, 20, 1007-1010. PDF

 

• Guzaev, A. P. and Manoharan, M. Novel reagents for terminal phosphorylation and thiophosphorylation of synthetic oligonucleotides. Tetrahedron Lett. 2001, 42, 4769-4773. PDF

 

• Guzaev, A. P. and Manoharan, M. Phosphoramidite Coupling to Oligonucleotides Bearing Unprotected Internucleosidic Phosphate Moieties. J. Org. Chem. 2001, 66, 1798-1804. PDF

 

• Guzaev, A. P. and Manoharan, M. 2-Benzamidoethyl Group – a Novel Type of Phosphate Protecting Group for Oligodeoxynucleotide Synthesis. J. Am. Chem. Soc. 2001, 123, 783-793. PDF

 

• Guzaev, A. P. and Manoharan, M. A Novel Phosphate Protection for Oligonucleotide Synthesis: the 2-[(1-Naphthyl)carbamoyloxy]ethyl (NCE) Group. Tetrahedron Lett. 2000, 41, 5623-5626. PDF

 

• Maier, M. A.; Guzaev, A. P.; and Manoharan, M. Synthesis of Chimeric Oligonucleotides Containing Phosphodiester, Phosphorothioate, and Phosphoramidate Linkages. Organic Lett. 2000, 2, 1819-1822. PDF

​​

• Bhat, B.; Balow, G.; Guzaev, A.; and Manoharan, M. Synthesis of Fully Protected Nucleoside – Folic Acid Conjugated Phosphoramidites and Their Incorporation into Antisense Oligonucleotides. Nucleosides & Nucleotides 1999, 18, 1471-1472.

​​

• Guzaev, A. and Manoharan, M. Synthesis of Oligonucleotide Conjugates with the aid of N-chloroacetamidohexyl Phosphoramidite Reagent. Nucleosides & Nucleotides 1999, 18, 1455-1456.

​​

• Guzaev, A.; Balow, G.; and Manoharan, M. Synthesis of Chimerical Oligonucleotides Containing Internucleosidic Phosphodiester and S-Pivaloyl Mercaptoethyl Phosphotriester Linkages. Nucleosides & Nucleotides 1999, 18, 1391-1392.

​​

• Guzaev, A.; Boyode, B.; Balow, G.; Tivel, K. L.; and Manoharan, M. Use of [4,6-di-14C]-5'-DMT-thymidine Phosphoramidite Reagent for the Radiolabeling of Synthetic Oligonucleotides. Nucleosides & Nucleotides 1999, 18, 1389-1390.

 

• Guzaev, A. and Lönnberg, H. Solid Support Synthesis of Ester Linked Hydrophobic Conjugates of Oligonucleotides. Tetrahedron 1999, 55, 9101-9116. PDF

 

• Wang, J.-C.; Just, G.; Guzaev, A. P.; Manoharan, M. Stereoselective Synthesis of a Cyano Alkylphosphonate by Intramolecular Rearrangement. J. Org. Chem. 1999, 64, 2595-2598. PDF

 

• Guzaev, A. and Manoharan, M. Conjugation of Oligonucleotides via an Electrophilic Tether: N-Chloroacetamidohexyl Phosphoramidite Reagent. Bioorg. Med. Chem. Letters 1998, 8, 3671-3676. PDF

 

• Guzaev, A.; Boyode, B.; Balow, G.; Tivel, K. L.; and Manoharan, M. Synthesis of 14C-Radiolabeled Oligonucleotides with a Novel Phosphoramidite Reagent. Bioorg. Med. Chem. Letters 1998, 8, 1123-1126. PDF

 

• Salo, H.; Guzaev, A.; and Lönnberg, H. Disulfide Tethered Solid Supports for Synthesis of Photoluminescent Oligonucleotide Conjugates: Hydrolytic Stability and Labeling on the Support. Bioconjugate Chem. 1998, 9, 365-371. PDF

 

• Guzaev, A. and Lönnberg, H. Bishydroxymethylation of the Active Methylene Group of 1,3-Dicarbonyl and Related Compounds. Synthesis 1997, 1281-1284. PDF

 

• Guzaev, A. and Lönnberg, H. A Novel Solid Support for Synthesis of 3'-Phosphorylated Chimeric Oligonucleotides Containing Internucleosidic Methyl Phosphotriester and Methylphosphonate Linkages. Tetrahedron Letters 1997, 38, 3989-3992. PDF

 

• Guzaev, A.; Salo, H.; Azhayev, A.; and Lönnberg, H. Synthesis of Oligonucleotide Analogues by Using Phosphoramidite Reagents Derived from 2,2-bis(hydroxymethyl)malonates. Coll. Czechoslovak Chem. Comm. 1996, 61, Special Issue, 226-229.

​​

• Salo, H.; Guzaev, A.; Azhayev, A.; and Lönnberg, H. Disulfide Tethered Solid Supports for Oligonucleotide Synthesis: Preparation and a Comparative Study on the Resistance to Ammonolysis. Coll. Czechoslovak Chem. Comm. 1996, 61, Special Issue, 110-111.

 

• Kuusela, S.; Guzaev, A.; and Lönnberg, H. Zn2+ Promoted Hydrolysis of Oligonucleotides. Coll. Czechoslovak Chem. Comm. 1996, 61, Special Issue, 30-32.

 

• Kuusela, S.; Guzaev, A.; and Lönnberg, H. Acceleration of the Zn2+ Promoted Phosphodiester Hydrolysis of Oligonucleotides by the       3'-Terminal Monophosphate Group: Intrastrand Participation over Several Nucleoside Units. J. Chem. Soc. Perkin Trans. II 1996, 1895-1899. PDF

 

• Guzaev, A.; Salo, H; Azhayev, A; Lönnberg, H. Novel Non-Nucleosidic Building Blocks for the Preparation of Multilabeled Oligonucleotides. Bioconjugate Chem. 1996, 7, 240-248. PDF

​​

• Senchenko, V. N.; Guzaev, A. P.; Boitsova, S. E.; Maiorov, V. A.; Dudich, I. V.; Shlyapnikov, S. V.; Karpeiskii, M. Ya. Preparation and Properties of Hybrid RNase S’ formed by S Protein and the S-S bond Conjugate of [Nle-13, Cys-20]S-Peptide with 3'-Thiopropyl Derivative of d(T)15. Mol. Biol. (Moscow) 1996, 30, 681-691.

​​

• Petrovskaya, L. E.; Kryukova, E. A.; Yakimov, S. A.; Wulfson, A. N.; Alibaeva, R. A.; Shingarova, L. N.; Guzaev, A. P.; Abramov, V. M.; and Korobko, V. G. Effect of Topography of the Signal Protease Cleavage Site on Secretion of Human Granulocite Macrophage Colony Stimulating Factor into Periplasm of Escherichia coli Cell. Bioorg. Khim. (Moscow) 1995, 21, 912-919. English translation: Russ. J. Bioorganic Chem., 1995, 21, 785-791.

 

• Azhayeva, E.; Azhayev, A.; Guzaev, A.; Lönnberg, H. Selective Binding of Looped Oligonucleotides to a Single- Stranded DNA and Its Influence on Replication in vitro. Nucleic Acids Res. 1995, 23, 4255-4261. PDF

 

• Guzaev, A.; Salo, H.; Azhayev, A.; Lönnberg, H. A New Approach for Chemical Phosphorylation of Oligonucleotides at the 5'-Terminus. Tetrahedron 1995, 51, 9375-9384. PDF

 

• Kuusela, S.; Azhayev, A.; Guzaev, A.; Lönnberg, H. The Effect of 3'-Terminal Monophosphate Group on Metal-Ion-Promoted Hydrolysis of Phosphodiester Bonds of Short Oligonucleotides. J. Chem. Soc. Perkin Trans. II 1995, 1197-1202. PDF

 

• Hovinen, J.; Guzaev, A.; Azhayeva, E.; Azhayev, A.; Lönnberg, H. Imidazole Tethered Oligodeoxyribonucleotides: Synthesis and RNA Cleaving Activity. J. Org. Chem. 1995, 60, 2205-2209. PDF

 

• Azhayeva, E.; Azhayev, A.; Guzaev, A.; Hovinen, J.; Lönnberg, H. Looped Oligonucleotides Form Stable Hybrid Complexes with a Single-stranded DNA. Nucleic Acids Res. 1995, 23, 1170-1176. PDF

​​

• Guzaev, A.; Hovinen, J.; Azhayev, A.; Lönnberg, H. A General Approach for the Hydroxy Group Functionalyzation of Synthetic Oligonucleotides. Nucleosides & Nucleotides 1995, 14, 833-837.

​​

• Hovinen, J.; Azhayev, A.; Guzaev, A.; Lönnberg, H. Synthesis of Analogues of 3'-Deoxypsicothymidine. Nucleosides & Nucleotides 1995, 14, 329-332.

 

• Hovinen, J.; Guzaev, A.; Azhayev, A.; Lönnberg, H. Novel Non-Nucleosidic Phosphoramidite Building Blocks for Versatile Functionalization of Oligonucleotides at Primary Hydroxyl Grous. J. Chem. Soc. Perkin Trans. I 1994, 2745-2749. PDF

 

• Guzaev, A.; Azhayeva, E.; Hovinen, J.; Azhayev, A.; Lönnberg, H. Synthesis and Primer Properties of Oligonucleotides Containing 3'-Deoxypsicothymidine Units, Labelled with Fluorescein at the 1'-Position. Bioconjugate Chem. 1994, 5, 501-503. PDF

​​

• Hovinen, J.; Guzaev, A.; Azhayev, A.; Lönnberg, H. Novel Solid Supports for the Preparation of 3'-Derivatized Oligonucleotides: Introduction of 3'-Alkylphosphate Tether Groups Bearing Amino, Carboxy, Carboxamido, and Mercapto Functionalities. Tetrahedron 1994, 50, 7203-7218. PDF

 

• Azhayev, A.; Guzaev, A.; Hovinen, J.; Mattinen, J.; Sillanpää, R.; Lönnberg, H. Synthesis and Properties of 3'- Deoxypsiconucleosides: Anomeric 1-(3'-deoxy-D-erythro-2-hexulofuranosyl) thymines and 9-(3-deoxy-D-erythro-2- hexulofuranosyl)adenines. Synthesis 1994, 396-400. PDF

 

• Hovinen, J.; Azhayeva, E.; Azhayev, A.; Guzaev, A.; Lönnberg, H. Synthesis of 3'-O-(aminoalkoxymethyl)thymidine 5'- triphosphates, Terminators of DNA Synthesis that Enable 3'-Labelling. J. Chem. Soc. Perkin Trans. I 1994, 211-217. PDF

 

• Hovinen, J.; Guzaev, A.; Azhayev, A.; Lönnberg, H. Synthesis of 3'-Functionalized Oligonucleotides on a Single Solid Support. Tetrahedron Lett. 1993, 34, 8169-8172. PDF

 

• Azhayev, A.; Gouzaev, A.; Hovinen, J.; Azhayeva, E.; Lönnberg, H. Analogues of Oligonucleotides Containing 3'- Deoxy-b-D psicothymidine. Tetrahedron Lett. 1993, 34, 6435-6438. PDF

 

• Hovinen, J.; Gouzaev, A. P.; Azhayev, A. V.; Lönnberg, H. A New Method to Prepare 3'-Modified Oligonucleotides. Tetrahedron Lett. 1993, 34, 5163-5166. PDF

​​

• Guzaev, A. P. An Efficient Synthesis of N2-isobutyryl-O6-[2-(4-nitrophenyl)ethyl]-5'-dimethoxytrityl-2'-deoxyguanosine. Nucleosides & Nucleotides 1992, 11, 1463-1466.

 

• Hakala, H.; Oivanen, M.; Saloniemi, E.; Gouzaev, A.; Lönnberg, H. Acid-Catalyzed Depurination of di, tri- and Polydeoxyribonucleotides: Effect of Molecular Environment on the Cleavage of Adenine Residue. J. Phys. Org. Chem. 1992, 5, 824-828. PDF

 

• Karlyshev, A. V.; Galyov, E. E.; Smirnov, O. Yu.; Guzayev, A. P.; Abramov, V. M.; Zav'yalov, V. P. A New Gene of the f1 Operon of Y.pestis Involved in the Capsule Biogenesis. FEBS Letters 1991, 297, 7780. PDF

​​

• Guzaev, A. P. An Efficient Synthesis of 3'-Mercaptoalkylated Oligodeoxyribonucleotides on the Universal Solid Support. Nucleic Acids Res. Symposium Series 1991, No 24, 236.

 

• Moskovkin, A. S.; Guzaev, A. P.; Miroshnichenko, I. V.; Botnikov, M. Ya.; Unkovskii, B. V. Mass Spectrometric Study of Products Resulting from Intramolecular Cyclization of 1,3-Amido Alcohols. 5,6-Dihydro-4H-1,3-oxazines and 2-Oxazolines. Khim. Geterotsikl. Soedin. 1988, 1539-1543 (in russian); CA 111: 96485w; Chem. Heterocycl. Compounds 1988, 24, 1277-1281 (Engl. Translation).

​

Back to top