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Sugar-modified Nucleoside Phosphoramidites

Abstract Light Projection
Chemical structure of 2'-OMe adenosine phosphoramidite (Product 71121) for modified oligonucleotide synthesis
p/n
Nucleoside
Base
R
71121
dA(bz)
Benzoyl protected Adenine
H
71122
dC(ac)
Acetyl protected Cytosine
H
71123
dG(ib)
iso-butyryl protected Guanine
H
71124
dT
Thymine
H
71125
2'-OMe A(bz)
Benzoyl protected Adenine
OMe
71126
2'-OMe C(ac)
Acetyl protected Cytosine
OMe
71127
2'-OMe G(ib)
iso-butyryl protected Guanine
OMe
71128
2'-OMe U
Uracil
OMe

Purity: 96% Minimum / Package: 1g bottle

Nucleosides with other base-protecting groups are available depending on customer specific requests. 

For price information of all p/n, please inquire (info@amchemicals.com)

Abstract Light Projection

Sugar-modified Nucleoside Phosphoramidites
Galactose

Chemical structure of 2'-OMe cytidine phosphoramidite (Product 72121) for modified oligonucleotide synthesis
p/n
Nucleoside
Base
R
72121
dA(bz)
Benzoyl protected Adenine
H
72122
dC(ac)
Acetyl protected Cytosine
H
72123
dG(ib)
iso-butyryl protected Guanine
H
72124
dT
Thymine
H
72125
2'-OMe A(bz)
Benzoyl protected Adenine
OMe
72126
2'-OMe C(ac)
Acetyl protected Cytosine
OMe
72127
2'-OMe G(ib)
iso-butyryl protected Guanine
OMe
72128
2'-OMe U
Uracil
OMe

Purity: 96% Minimum / Package: 1g bottle

Nucleosides with other base-protecting groups are available depending on customer specific requests. 

For price information of all p/n, please inquire (info@amchemicals.com)

Abstract Light Projection

Sugar-modified Nucleoside Phosphoramidites
GlcNAc

Chemical structure of 2'-OMe guanosine phosphoramidite (Product 73121) for modified oligonucleotide synthesis
p/n
Nucleoside
Base
R
73121
dA(bz)
Benzoyl protected Adenine
H
73122
dC(ac)
Acetyl protected Cytosine
H
73123
dG(ib)
iso-butyryl protected Guanine
H
73124
dT
Thymine
H
73125
2'-OMe A(bz)
Benzoyl protected Adenine
OMe
73126
2'-OMe C(ac)
Acetyl protected Cytosine
OMe
73127
2'-OMe G(ib)
iso-butyryl protected Guanine
OMe
73128
2'-OMe U
Uracil
OMe

Purity: 96% Minimum / Package: 1g bottle

Nucleosides with other base-protecting groups are available depending on customer specific requests. 

For price information of all p/n, please inquire (info@amchemicals.com)

Abstract Light Projection

Sugar-modified Nucleoside Phosphoramidites
GalNAc

Chemical structure of 2'-OMe uridine phosphoramidite (Product 74121) for modified oligonucleotide synthesis
p/n
Nucleoside
Base
R
74121
dA(bz)
Benzoyl protected Adenosine
H
74122
dC(ac)
Acetyl protected Cytosine
H
74123
dG(ib)
iso-butyryl protected Guanine
H
74124
dT
Thymine
H
74125
2'-OMe A(bz)
Benzoyl protected Adenosine
OMe
74126
2'-OMe C(ac)
Acetyl protected Cytosine
OMe
74127
2'-OMe G(ib)
iso-butyryl protected Guanine
OMe
74128
2'-OMe U
Uracil
OMe

Purity: 96% Minimum / Package: 1g bottle

Nucleosides with other base-protecting groups are available depending on customer specific requests. 

For price information of all p/n, please inquire (info@amchemicals.com)

Gentle Water Spray

​Product Details

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​Product Features

​

  • Specialty nucleoside phosphoramidites (DMT-protected)

  • Modified saccharide attached to the phosphoramidites via a triethylene glycol linker

  • Incorporation of the phosphoramidites at terminal or any desired position of the oligonucleotide

  • Compatible with standard oligonucleotide synthesis protocols

  • Requires the standard coupling protocols

  • The phosphotriester moieties introduced may require special care and conditions at the deprotection step

  • Synthetically feasible for scale-up and manufacturing

  • Synthesis of DNA oligos with P=O and P=S backbones

  • Synthesis of RNA oligos with P=O and P=S backbones​

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