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Sequential couplings yield trivalent GalNAc-oligo conjugate
1. Couple with GalNAc phosphoramidite,
p/n 51210
2. Oxidation (X=O) or
Sulfurization (X=S) with
p/n 30000
1. One more coupling cycle with
GalNAc phosphoramidite,
p/n 51210
2. Assembly of the desired oligonucleotide;
3. Basic deprotection
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