AM Chemicals

1. Couple with GalNAc phosphoramidite, p/n 51210

2. Oxidation (X=O) or

    Sulfurization (X=S) with p/n 30000

1. One more coupling cycle with

   GalNAc phosphoramidite, p/n 51210

2. Assembly of the desired oligonucleotide;

3. Basic deprotection