DMT-protected Universal Solid Supports
DMT-protected Universal Solid Supports
Labile C3 Linker
CAS #: 730963-35-6
p/n | Solid Phase Material | Price, $/50g | Price, $/100g | Max Loading |
|---|---|---|---|---|
01211 | CPG 500 | $2,850 | $5,085 | 85 umol/g |
01212 | CPG 1000 | $2,850 | $5,085 | 50 umol/g |
01213 | Polystyrene | $2,940 | $5,190 | 100 umol/g |
01214 | CPG 1400 | $2,850 | $5,085 | 35 umol/g |
Please specify your desired loading with a span of 5 umol/g (i.e. 30-35 umol/g)
p/n | Solid Phase Material | Price, $/50g | Price, $/100g | Max Loading |
|---|---|---|---|---|
01221 | CPG 500 | $2,850 | $5,085 | 85 umol/g |
01222 | CPG 1000 | $2,850 | $5,085 | 50 umol/g |
01223 | Polystyrene | $2,940 | $5,190 | 100 umol/g |
01224 | CPG 1400 | $2,850 | $5,085 | 35 umol/g |
Please specify your desired loading with a span of 5 umol/g (i.e. 30-35 umol/g)
p/n | Solid Phase Material | Price, $/50g | Price, $/100g | Max Loading |
|---|---|---|---|---|
01231 | CPG 500 | $2,995 | $5,355 | 85 umol/g |
01232 | CPG 1000 | $2,995 | $5,355 | 50 umol/g |
01233 | Polystyrene | $3,045 | $5,460 | 100 umol/g |
01234 | CPG 1400 | $2,995 | $5,355 | 35 umol/g |
01235 | CPG 2000 | $3,045 | $5,460 | 28 umol/g * |
01236 | CPG 3000 | $3,150 | $5,660 | 23 umol/g * |
Please specify your desired loading with a span of 5 umol/g (i.e. 30-35 umol/g)
*Max loading as allowed by the available surface area
Product Details
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User Guide for Universal Solid Supports (PDF)
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For price info on package size of above 100 g for all p/n, please inquire (info@amchemicals.com)
Product Features
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Compatibility with standard oligonucleotide synthesis protocols
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Requires no special treatments or reaction conditions
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Multiple ligand attachments (5’-end, 3’-end or at both the ends) to oligos
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Used for small, medium, and large scale oligo synthesis
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Synthesis of DNA, 2’-OMe (P=O and P=S backbones) oligos
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Synthesis of RNA (P=O and P=S backbones) oligos
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Numerous selections of universal solid supports offered:
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Solid phase material – CPG (500 Å, 1000 Å, 1400 Å, or 2000 Å), and Polystyrene
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Succinyl (labile) or amide (stable) linker attachment to universal solid support
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The state of the hydroxy group –DMT-protected
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Simplified inventory control
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Single universal solid support versus several nucleosidic supports
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Regulatory agency advantage – universal solid support deemed as raw material
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Scientific publications demonstrating the robustness of universal solid supports
1. Guzaev, A. P. and Manoharan, M. A Conformationally Preorganized Universal Solid Support for Efficient Oligonucleotide Synthesis. J. Am. Chem. Soc. 2003, 125, 2380-2381
2. Kumar, R. K., Guzaev, A. P., Rentel, C., Ravikumar, V. T. Efficient Synthesis of Antisense Phosphorothioate Oligonucleotides Using a Universal Solid Support. Tetrahedron 2006, 62, 4528-4534