Non-nucleosidic Modifier Phosphoramidites
for Targeted Cellular Uptake of Oligonucleotides
Non-nucleosidic Modifier Phosphoramidite
GalNAc
CAS #: 2172953-01-2
[How to make 3 GalNAc cluster at 5'-end DEMO]
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51210 | $1,600 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
For a very similar compound and small quantity requirements, please contact Glen Research
Non-nucleosidic Modifier Phosphoramidite
Cholesteryl
CAS #: 2172953-03-4
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51230 | $1,425 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
Non-nucleosidic Modifier Phosphoramidite
DL-tocopherol
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51231 | $2,185 |
Purity: 96% Minimum / Package: 1g bottle
Diluent: Anhydrous Acetonitrile/Dichloromethane 1:3 (v/v)
For other packaging requirements, please contact (info@amchemicals.com)
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51232 | $1,425 |
Purity: 96% Minimum / Package: 1g bottle
Diluent: Anhydrous Acetonitrile/Dichloromethane 1:3 (v/v)
For other packaging requirements, please contact (info@amchemicals.com)
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51233 | $1,885 |
Purity: 96% Minimum / Package: 1g bottle
Diluent: Anhydrous Acetonitrile/Dichloromethane 1:3 (v/v)
For other packaging requirements, please contact (info@amchemicals.com)
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51234 | $2,000 |
Purity: 96% Minimum / Package: 1g bottle
Diluent: Anhydrous Acetonitrile/Dichloromethane 1:3 (v/v)
For other packaging requirements, please contact (info@amchemicals.com)
Product Features
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Novel, achiral non-nucleosidic building blocks (TMT-protected)
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Amenable for single or multi-labeled oligo synthesis
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Incorporation of the phosphoramidites at terminal or any desired position of the oligonucleotide
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Compatible with standard oligonucleotide synthesis protocols
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Free of structural motifs that lead to undesired side reactions at the deprotection step
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Requires no special treatments or reaction conditions
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Synthetically feasible for scale-up and manufacturing
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Synthesis of DNA oligos with P=O and P=S backbones
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Synthesis of RNA oligos with P=O and P=S backbones
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Numerous other ligands are available upon customer’s request
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Scientific publications** on the design, synthesis of non-nucleosidic phosphoramidites and preparation of ligand-oligonucleotides conjugates
** 1. Guzaev, A. P. Oral presentation delivered at XXII International Round Table, Paris, July 2016
2. Gogoi, K., Vvedensky, V., and Guzaev, A.P. Poster presented at TIDES 2017 Conference, San Diego, May 2017 (PDF)