Non-nucleosidic Modifier Phosphoramidites
for Introducing Functional and Reporter Groups
Non-nucleosidic Modifier Phosphoramidite
TFA Amino
CAS #: 2172952-41-7
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51220 | $1,400 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
Non-nucleosidic Modifier Phosphoramidite
Alkyne
CAS #: 2172952-92-8
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51240 | $1,335 |
For other packaging requirements, please contact (info@amchemicals.com)
Non-nucleosidic Modifier Phosphoramidite
Fluorescein
CAS #: 2172953-07-8
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51250 | $2,060 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
Non-nucleosidic Modifier Phosphoramidite
Biotin
CAS #: 2172953-75-0
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51260 | $3,270 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
Non-nucleosidic Modifier Phosphoramidite
Pyrene
CAS #: 2172952-94-0
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51270 | $1,655 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
Non-nucleosidic Modifier Phosphoramidite
Dabsyl
CAS #: 2172953-10-3
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51280 | $1,815 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
Non-nucleosidic Modifier Phosphoramidite
Dabcyl
CAS #: 2172953-05-6
TMT denotes the trimethoxytrityl protecting group
p/n | Price, $/g |
|---|---|
51290 | $1,815 |
Purity: 96% Minimum / Package: 1g bottle
For other packaging requirements, please contact (info@amchemicals.com)
Product Features
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Novel, achiral non-nucleosidic building blocks (TMT-protected)
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Amenable for single or multi-labeled oligo synthesis
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Incorporation of the phosphoramidites at terminal or any desired position of the oligonucleotide
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Compatible with standard oligonucleotide synthesis protocols
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Free of structural motifs that lead to undesired side reactions at the deprotection step
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Requires no special treatments or reaction conditions
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Synthetically feasible for scale-up and manufacturing
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Synthesis of DNA oligos with P=O and P=S backbones
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Synthesis of RNA oligos with P=O and P=S backbones
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Numerous other ligands are available upon customer’s request
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Scientific publications** on the design, synthesis of non-nucleosidic phosphoramidites and preparation of ligand-oligonucleotides conjugates
** 1. Guzaev, A. P. Oral presentation delivered at XXII International Round Table, Paris, July 2016
2. Gogoi, K., Vvedensky, V., and Guzaev, A.P. Poster presented at TIDES 2017 Conference, San Diego, May 2017 (PDF)